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Showing 1 - 9Racial Differences in the Risk of Second Breast Tumors Reported in Women With Ductal Carcinoma in Situ
Regardless of age at diagnosis, type of treatment, tumor grade or size, and tumor histology, black and Hispanic women had a higher risk of second ipsilateral breast tumors than did white women after ductal carcinoma in situ, according to the results of a large registry study presented by Liu et al...
More Accurate Identification of Molecular Subgroups May Better Guide Neoadjuvant Treatment of Breast Cancer
BluePrint in combination with MammaPrint molecular subtyping reclassified more than 20% of breast cancer patients into a different subgroup compared with conventional assessment, according to the results of the prospective Neoadjuvant Breast Registry Symphony Trial (NBRST). In Annals of Surgical...
Study Reveals Long-Term Benefits With Prone Hypofractionated Radiation Therapy and a Concurrent Boost in Early-Stage Breast Cancer
Prone accelerated intensity-modulated radiation therapy with a concomitant boost produced excellent local tumor control and cosmesis while sparing normal tissues in women with early-stage breast cancer, according to the 5-year study results reported by Osa et al in the International Journal of...
Initial Treatment of Ductal Carcinoma in Situ May Affect Subsequent Treatment of Tumor Recurrences After Surgery
The use of radiotherapy for the index ductal carcinoma in situ (DCIS) may affect subsequent treatment of tumor recurrences and complications after breast-conserving surgery, reported Greenberg et al in the Annals of Surgical Oncology. Based on the results of this retrospective cohort study, the...
Proactive Patient-Centered Program May Reduce the Risk of Lymphedema in Survivors of Breast Cancer
A patient-centered educational and behavioral program focusing on self-care strategies appears to be an effective way to reduce the risk of lymphedema in survivors of breast cancer, according to the results of a prospective study by Fu et al at New York University. These findings, reported in the...
Wider Surgical Margins Do Not Appear To Reduce Local Recurrence Rates in Triple-Negative Breast Cancer
Wider surgical margins did not reduce the rate of local recurrence in women with triple-negative breast cancer treated with breast-conserving therapy, according to the results of a study published in the Annals of Surgical Oncology. Pilewskie et al reported that their data support the definition of ...
Nonsignificant Reduction in Breast Cancer Risk Seen With Low-Dose Tamoxifen in Postmenopausal Hormone Replacement Therapy Users
In postmenopausal women receiving hormone replacement therapy, low-dose tamoxifen did not significantly reduce the risk of breast cancer but did increase climacteric symptoms, according to the phase III study results presented by DeCensi et al in the Annals of Oncology. However, beneficial trends...
Hypercholesterolemia May Drive the Growth of Breast Cancer
High levels of the cholesterol metabolite 27-hydroxycholesterol seem to function like estrogen and may independently drive the growth of breast cancer, according to the findings of a preclinical study by Nelson et al published in Science. They also found a possible connection between...
Timing and Choice of Treatment May Affect the Quality of Life of Young Breast Cancer Survivors
The choice and timing of therapeutic interventions may significantly affect the quality of life of young breast cancer survivors in the short term, although other quality-of-life domains such as family relationships may not be negatively impacted after treatment. These findings were reported by...
